- River Academy and Quillen Day Treatment Program – Education and guidance for Holston Home residents and day students.
- Bewley Center – Residential program for adolescent girls.
- Hull Residence – Residential program for adolescent girls.
- Walter B. and Theresa Brumit Center – Apartment-style residential center to prepare young adults for independent living.
- Wiley Center – Residential program for boys ages 11 to 18.
